Physicochemical and in vitro cytotoxic properties of chitosan from mushroom species (Boletus bovinus and Laccaria laccata)

Oberemko, Alona; Salaberria, Asier M.; Saulė, Rita; Saulis, Gintautas; Kaya, Murat; Labidi, Jalel; Baublys, Vykintas

doi:10.1016/j.carbpol.2019.05.073

Use this url to cite publication: https://hdl.handle.net/20.500.12259/100989

Physicochemical and in vitro cytotoxic properties of chitosan from mushroom species (Boletus bovinus and Laccaria laccata)

Type of publication

Straipsnis Web of Science ir Scopus duomenų bazėje / Article in Web of Science and Scopus database (S1)

Author(s)

Author	Affiliation
Oberemko, Alona	Gamtos mokslų fakultetas / Faculty of Natural Sciences	LT
Salaberria, Asier M.	University of the Basque Country (UPV/EHU), Spain	ES
Saulė, Rita	Biologijos katedra / Department of Biology	LT
Saulis, Gintautas	Biologijos katedra / Department of Biology	LT
Kaya, Murat	Aksaray University, Turkey	TR
Labidi, Jalel	University of the Basque Country (UPV/EHU), Spain	ES
Baublys, Vykintas	Biologijos katedra / Department of Biology	LT

Title

Physicochemical and in vitro cytotoxic properties of chitosan from mushroom species (Boletus bovinus and Laccaria laccata)

[en]

Is part of

Carbohydrate polymers. Amsterdam : Elsevier, 2019, Vol. 221

Date Issued

Date
2019

Publisher

Amsterdam : Elsevier

Publisher (trusted)

Elsevier Science

Is Referenced by

Science Citation Index Expanded (Web of Science)

Academic Search Complete

Scopus

Extent

p. 1-9

URI

URI
https://doi.org/10.1016/j.carbpol.2019.05.073
https://hdl.handle.net/20.500.12259/100989

DOI

10.1016/j.carbpol.2019.05.073

Area of Science

Field of Science

Keywords (lt)

Keywords (en)

Abstract (en)

Chitosan samples from two mushroom species (Boletus bovinus, Laccaria laccata) were obtained and characterized by viscosimetry, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), elemental analyses (EA), nuclear magnetic resonance spectroscopy (C-13 NMR), X-ray diffraction (XRD) and thermogravimetric (TGA) analyses. Properties of the fungal chitosan samples were compared to commercial low-molecular weight chitosan, crustacean chitosan (Cervimunida john) and chitosan obtained from an insect (Hilobius abietis). Additionally, the cytotoxic properties of chitosan in vitro on cancerous hepatoma and non-cancerous ovary cells cultivated on films with different chitosan concentrations was evaluated. As a conclusion, this study clearly revealed that low-molecular weight chitosan films and solutions with high degree of deacetylation can act cytotoxically on both tumor MH-22A and normal CHO cells in vitro. Consequently, this work may be useful for further investigations of natural anticancer products in medical areas.