The article discusses the possibilities of the resilience of organizations in the context of a learning organization and presents the results of a survey of the leaders of regional public organizations, on the basis of which the factors of the resilience of organizations are ranked according to importance. The study results have revealed that NGOs further away from regional centres tend to focus on routine management aspects, enabling the members of the organization to communicate and collaborate effectively, meanwhile the development of the members, an essential resilience factor, was not considered as highly important.

The article defines the links between the resilience of organizations and the social sustainability of regions, describes the difficulties and management challenges faced by organizations in conditions of uncertainty. The theoretical part reveals the concept of regional social sustainability, discusses the strengthening of the resilience of organizations in the context of regional social sustainability, presents the challenges of organizational management in an environment of uncertainty. The study identifies the ability of organizations to act in the face of uncertainties and reveals the management challenges faced by organizations operating in an environment of uncertainties.