The general purpose of this study was to present a newly developed system designed for monitoring of cardiovascular and physical activity changes. The hardware system consists of the device for registration of ECG and accelerometers signals and wireless transmission to computer. The coach software works in two modes: on-line version is used during training and offline version is designed for detailed data analysis after training. Subjects performed six different locomotors tasks: 1 – unrestrained walking; 2 – short-step walking; 3 – long-step walking; 4 – unrestrained running; 5 – short-step running; 6 – long-step running along a standardized stadium circuit; and each locomotor activity follow-up for a 180 seconds. The present investigation also confirmed the large inter-individual variation of acceleration while performing the same exercise. The data obtained during the study showed that assessments by accelerometers overestimated intensity of physical activity during short-step walking and running, and underestimated it during the same locomotion performed by long-step. The results obtained during the investigations allows to conclude that developed ECG and motion activity monitoring system with two packages of software allows to measure and asses the cardiovascular and physical activity changes during the walking and running tasks.