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Type of publication: Straipsnis Clarivate Analytics Web of Science ar/ir Scopus / Article in Clarivate Analytics Web of Science or / and Scopus (S1)
Field of Science: Ekologija ir aplinkotyra / Ecology and environmental sciences (N012)
Author(s): Montazeri, Parisa;Thomsen, Cathrine;Casas, Maribel;Bont, Jeroen de;Haug, Line S;Maitre, Léa;Papadopoulou, Eleni;Sakhi, Amrit K;Slama, Rémy;Saulnier, Pierre-Jean;Urquiza, Jose;Gražulevičienė, Regina;Andrušaitytė, Sandra;McEachan, Rosie;Wright, John;Chatzi, Leda;Basagaña, Xavier;Vrijheid, Martine
Title: Socioeconomic position and exposure to multiple environmental chemical contaminants in six European mother-child cohorts
Is part of: International journal of hygiene and environmental health. Amsterdam : Elsevier B.V., 2019, vol. 222, iss. 5
Extent: p. 864-872
Date: 2019
Note: The research leading to these results has received funding: Dr.Maribel Casas received funding from Instituto de Salud Carlos III (Ministry of Economy and Competitiveness) (MS16/00128). The INMA (Environment and Childhood) Sabadell cohort and biomarker mea-surements were funded by grants from Instituto de Salud Carlos III (RedINMA G03/176; CB06/02/0041; PI041436; PI081151 incl. FEDERfunds; PI12/01890 incl. FEDER funds; CP13/00054 incl. FEDER-funds),CIBERESP, Generalitat de Catalunya-CIRIT 1999SGR 00241,Generalitat de Catalunya-AGAUR (2009 SGR 501, 2014 SGR 822),Fundació La marató de TV3 (090430), Spanish Ministry of Economy and Competitiveness (SAF2012-32991 incl. FEDER funds)
Keywords: Chemical contaminant;Environment;Childhood life
Abstract: Background:Human exposure to environmental chemical contaminants at critical periods of development can lead to lifelong health consequences. Traditionally, socioeconomically disadvantaged groups are thought to experience highercontaminant exposures; however, this relationship may not hold for all contaminants. Methods:Using data from six European birth cohorts (1301 mother-child pairs), we determined biomarkers of exposure to 41 contaminants in biological samplesfrom children (6–12 years) and their mothers during pregnancy, including organochlorine compounds (OCs), polybrominated diphenyl ethers (PBDEs), per- andpolyfluoroalkyl substances (PFASs), metals, phthalate metabolites, phenols, and organophosphate (OP) pesticide metabolites. We analyzed these biomarkers withseveral socioeconomic position (SEP) indicators (maternal education, employment status and family affluence scale).Results:Higher SEP was associated with higher concentrations of several chemicals during pregnancy, including certain PFASs, mercury, arsenic, several phenols,and OP pesticides. Similarly, childhood concentrations of OCs, PFASs, mercury, arsenic, and bisphenol A were higher in higher SEP groups. Conversely, cadmiumexposure during pregnancy and exposure to lead and phthalate metabolites in childhood were higher in lower SEP. Principal components representing multiplepollutant exposures showed similar association with SEP.Conclusions:This study demonstrates that environmental chemical contaminant exposure during fetal and childhood life is not exclusively associated to lower SEP and that for several contaminants higher SEP groups incur higher exposure levels
Affiliation(s): Aplinkotyros katedra
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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