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Type of publication: Konferencijų tezės nerecenzuojamuose leidiniuose / Conference theses in non-peer-reviewed publications (T2)
Field of Science: Ekologija ir aplinkotyra / Ecology and environmental sciences (N012)
Author(s): Andrušaitytė, Sandra;Gražulevičienė, Regina
Title: Maternal occupational exposure and breastfeeding impact on programming child allergy
Is part of: Environmental health perspectives. Research Triangle Park, USA : National Institute of Environmental Health Sciences, 2016, vol. 124
Extent: p. 142-142
Date: 2016
Note: ISSN 1552-9924 (electronic) ; Abstract Number: P1-142 | ID: 3123. EHP : 28th annual conference International Society for Environmental Epidemiology "Old and new risks: challenges for environmental epidemiology" : Rome, Italy, 1-4 September 2016 : supplements
Keywords: Child allergy;Chemical substances;Breastfeeding
Abstract: Introduction. Epidemiologic data suggest a possible association between maternal exposure to chemical substances and risk of childhood allergy in offspring. The overall beneficial effects of breastfeeding for infants’ growth, immunity, and development have been well documented, but its role in allergy prevention is controversial. The purpose of this study was to assess the effect of maternal occupational exposure to chemical substances on programming allergy in 4–6 years children and to evaluate breastfeeding impact on these associations. Methods. This nested cases-control study included 645 mother-children pairs. Allergy was assessed by the standardized questionnaires. Logistic regression models were fitted to examine the associations as odds ratios (OR) between maternal occupational exposure, breastfeeding duration and the risk of allergy adjusted for relevant covariates. Results. As many as 67.0% of the mothers reported having occupational exposure to chemical substances more than 1 year before pregnancy. Children of mothers exposed at work to chemical substances had increased prevalence of allergy at 4–6 years age comparing with not exposed (32.6% and 25.0%, accordingly). Occupationally exposed to chemical substances mothers breastfeeding more than 3 months increased 4–6 years children allergy risk by 59 %, adjusted OR 1.59; 95% CI 0.80–3.16. These associations were robust to adjustment for covariates associated with allergy, such as maternal education, smoking during pregnancy, chronic disease, child’s gender, and low birth weight. Conclusions. Occupationally exposed to chemical substances mothers’ breastfeeding may be a predictor of allergy throughout the developmental trajectory of childhood. Further investigation is needed to elucidate the influence of chemical substances and breastfeeding on childhood allergy
Affiliation(s): Aplinkotyros katedra
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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