Use this url to cite publication: https://hdl.handle.net/20.500.12259/44235
Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes
Type of publication
Straipsnis Web of Science ir Scopus duomenų bazėje / Article in Web of Science and Scopus database (S1)
Author(s)
Author | Affiliation | |
---|---|---|
Bustamante, Mariona | ||
Title [en]
Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes
Is part of
BJOG : an international journal of obstetrics and gynaecology. Oxford : Blackwell Science, 2012, vol. 119, iss. 9
Date Issued
Date |
---|
2012 |
Publisher
Oxford : Blackwell Science
Is Referenced by
Extent
p. 1141–1146
Abstract (en)
A nested case–control association study was designed to investigate the influence of maternal and fetal copy number variants (CNVs) on reproductive outcomes. Genotypes of ten CNVs encompassing GST and CYP genes were assessed. Significant associations were only found for child CNV genotypes. In particular, the child GSTM1 insertion allele was associated with prematurity protection (odds ratio, 95% CI: 0.67, 0.51–0.89; P < 0.01), whereas the child GSTT2B insertion allele was associated with an increased risk of being small for gestational age (odds ratio, 95% CI: 1.33, 1.07–1.67; P = 0.01). The study highlights the role of the fetal genome in prenatal development and also the need to analyse CNVs in a systematic manner.
Type of document
type::text::journal::journal article::research article
Language
Anglų / English (en)
Coverage Spatial
Jungtinė Karalystė / United Kingdom of Great Britain and Northern Ireland (GB)
ISSN (of the container)
1470-0328
WOS
WOS:000306221000015
Other Identifier(s)
VDU02-000012148
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 3.76 | 2.326 | 2.326 | 2.326 | 1 | 1.617 | 2012 | Q1 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 3.76 | 2.326 | 2.326 | 2.326 | 1 | 1.617 | 2012 | Q1 |
Journal | Cite Score | SNIP | SJR | Year | Quartile |
---|---|---|---|---|---|
BJOG: An International Journal of Obstetrics and Gynaecology | 7.3 | 1.957 | 1.794 | 2012 | Q1 |