Antifungal effect of some herbal ingredients: menthol, cinnamal, citral, eugenol, d-limonen, linalol

Abstract

The antifungal activities of extract with some ingredients (menthol, cinnamal, citral, eugenol, d-limonen, linalol) have been demonstrated against fungi Aspergillus fumigatus, Penicillium chrysogenum, Cladosporium cladosporoides, Alternaria alternata. The composition of phytochemicals was analyzed by gas chromatography mass spectrometry. The minimum inhibitory concentrations (MIC) and minimum fungicidal concentration (MFC) were determined by serial microdilution method. The results indicated inhibitory effects of the extracts on the tested fungi. The minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values of the tested agents were between 0.25 and 10%. This extract with some ingredients was found to have a wide spectrum of activity against all fungi examined in this study and may be proposed in therapeutic or hygienic contexts