We report herein on the results of N- and O-alkylation of 5-cyano-2-methylsulfanyl-4(3H)-pyrimidinone with 4-substituted o>-bromoacetophenones. Synthesized N-(phenacyl)-4-pyrimidinones and 4-(phenacyloxy)pyrimidines with suitable substituents in pyrimidine ring are versatile synthons for the preparation of fused pyrimidine heterocycles.
Type of document
type::text::conference object::conference proceedings::conference paper