Please use this identifier to cite or link to this item:https://hdl.handle.net/20.500.12259/90411
Type of publication: research article
Type of publication (PDB): Straipsnis Clarivate Analytics Web of Science / Article in Clarivate Analytics Web of Science (S1)
Field of Science: Gyvūnų mokslai / Animal sciences (A003)
Author(s): Cicėnas, Jonas;Tamošaitis, Linas;Kvederavičiūtė, Kotryna;Tarvydas, Ričardas;Staniutė, Gintarė;Kalyan, Karthik;Meškinytė-Kaušilienė, Edita;Stankevičius, Vaidotas;Valius, Mindaugas
Title: KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma
Is part of: Medical oncology. Totowa : Humana Press, 2017, vol. 34, no 2
Extent: p. 1-11
Date: 2017
Note: eISSN 1559-131X
Abstract: Cancers are the group of diseases, which arise because of the uncontrolled behavior of some of the genes in our cells. There are possibilities of gene amplifications, overexpressions, deletions and other anomalies which might lead to the development and spread of cancer. One of the most dangerous ways to the cancers is the mutations of the genes. The mutated genes can start unstoppable proliferation of cells, their uncontrolled motility, protection from apoptosis, the DNA mutation enhancement as well as other anomalies, leading to the cancer. This review focuses on the genes, which are frequently mutated in various cancers and are known to be important in the advance and progression of colorectal cancer and melanoma, namely KRAS, NRAS and BRAF
Internet: http://link.springer.com/journal/12032/34/2/page/1
Affiliation(s): Nacionalinis vėžio institutas
University of Bern, Switzerland
Vilniaus universitetas
Vytauto Didžiojo universitetas
Žemės ūkio akademija
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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