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Type of publication: Straipsnis recenzuojamoje užsienio tarptautinės konferencijos medžiagoje / Article in peer-reviewed foreign international conference proceedings (P1d)
Field of Science: Ekologija ir aplinkotyra / Ecology and environmental sciences (N012)
Author(s): Chopra, Sonam;Šatkauskas, Saulius
Title: Electrotransfer of cytokine genes for cancer treatment
Is part of: Innovations in science and education: CBU international conference, March 21-23, 2018, Praha: book of proceedings, Vol. 6 / editors Petr Hájek, Ondřej Vít. Praha: CBU Research Institute s.r.o., 2018
Extent: p. 1036-1041
Date: 2018
Note: Online ISSN 1805-9961
Keywords: Gene electrotransfer;Electroporation;Cytokine;Cancer
ISBN: 9788027050376
Abstract: Gene electrotransfer, which designates the combination of gene transfer and electroporation, is a physical method for transfecting genes into cells and tissues. Many reports for the utilization of this techniques in animals confirmed that gene electrotransfer is a safe and efficient method. One of the major advantages of electrogene therapy is that it does not result in systemic toxicity. Gene electrotransfer (GET) of plasmids encoding cytokines has been shown to generate a potent anti-tumor effect. Delivery of plasmids encoding cytokines induces not only a local immune response but a systemic one as well. Cytokines can be used to stimulate host inflammatory responses and immunity to cancers. This review aims to summarize preclinically tested cytokine genes with the help of electroporation for cancer treatment
Affiliation(s): Biologijos katedra
Gamtos mokslų fakultetas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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