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Type of publication: research article
Type of publication (PDB): Straipsnis konferencijos medžiagoje Clarivate Analytics Web of Science ar/ir Scopus / Article in Clarivate Analytics Web of Science or Scopus DB conference proceedings (P1a)
Field of Science: Biologija / Biology (N010);Fizika / Physics (N002)
Author(s): Staliulionytė, Miglė;Ruzgys, Paulius;Germanas, Darius;Mickevičius, Saulius
Title: Evaluation of low-dose neutron impact on irradiated CHO cells
Is part of: Medical physics in the Baltic states : proceedings of the 13th international conference on medical physics, Kaunas, Lithuania, 9-11 November, 2017. Kaunas : Kaunas University of Technology, 2017, 13
Extent: p. 118-121
Date: 2017
Keywords: Cells;Neutron;Clonogenic assay
Abstract: Neutron interaction with biological tissues causes cell structural and functional changes that may lead to the death of cancerous cells but also may initiate radiation induced cancer due to the damages of healthy ones. Since neutron therapy is one of the cancer treatment methods it is important to investigate low dose radiation impact on healthy cells present in the irradiation field. The work was conducted in order to develop an appropriate methodology to estimate cell viability changes after their irradiation to neutrons. Chinese hamster ovary cells (CHO) were used for the experiments. Cells have been irradiated to 138 mSv, 246 mSv and 328mSv neutron doses in isotope based neutron generator at the Center for Physical Sciences and Technology (FTMC) Clonogenic assay was used to determine the viability of cells after irradiation. Since irradiation was performed in another city, the influence of transportation on the viability of cells was also evaluated. Results of investigation of neutron irradiated cells are discussed and cell evaluation methodology is provided in this article
Affiliation(s): Biologijos katedra
Fizikos katedra
Fizinių ir technologijos mokslų centro Fizikos institutas
Kauno technologijos universitetas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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