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dc.contributor.authorSerapinas, Danielius-
dc.contributor.authorNarbekovas, Andrius-
dc.contributor.authorJuškevičius, Jonas-
dc.description.abstractIn vitro fertilisation (IVF) and other assisted reproductive technologies (ART) are effective treatments for infertility and are widely provided in developed countries. However recent scientific publications suggest that there is an elevated risk of major structural malformations, imprinting defects and such syndromes as Prader-Willy, Angelman, Wiedeman-Beckwith.The aim of the study was to analyse if ART are associated with increased risk ofgenotoxicy for chromosomal nondisjunction in meiosis. Study included analysis of 50 families that prenatally were diagnosed chromosomal anomalies (Down, Turner, Klinefelter, Edwards, Patausyndrome). And control group included 70 families with healthy children.The results of present study showed, that in chromosomal anomalies group three cases of children with chromosomal anomalies were conceived after ART. In control group all healthy children were conceived naturally (p<0.05). The study also showed a statistically significantrelationshipbetween:olderage of the woman (> 35 years old)and theoccurrence oftrisomy (p<0.05). The number of observed pathological cases is not so big to make exact conclusions, but results of present study supports hypothesis, that ART are associated with greater risk of chromosomal anomalies in conceived childrenen
dc.description.sponsorshipLietuvos sveikatos mokslų universitetas. Medicinos akademija-
dc.description.sponsorshipMykolo Romerio universitetas-
dc.format.extentp. 112-117-
dc.relation.ispartofWulfenia. Klagenfurt : Landesmuseum Karnten, 2014, vol. 21, no. 1-
dc.relation.isreferencedbyElsevier Biobase-
dc.subjectInfertility, femaleen
dc.subjectReproductive techniques, assisteden
dc.subjectFertilization in Vitroen
dc.subjectChromosome disordersen
dc.subjectPrenatal diagnosisen
dc.subject.otherMedicina / Medicine (M001)-
dc.titleResults of prenatal tests in pregnancies after assisted reproductive technologiesen
dc.typeStraipsnis kitose duomenų bazėse / Article in other databases (S4)-
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Appears in Collections:Universiteto mokslo publikacijos / University Research Publications
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