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Type of publication: conference paper
Type of publication (PDB): Konferencijų tezės nerecenzuojamuose leidiniuose / Conference theses in non-peer-reviewed publications (T2)
Field of Science: Biologija / Biology (N010);Farmacija / Pharmacy (M003)
Author(s): Mickienė, Rūta;Šalomskas, Algirdas;Lelešius, Raimundas;Karpovaitė, Agneta;Drevinskas, Tomas;Tiso, Nicola;Ragažinskienė, Ona;Maruška, Audrius Sigitas
Title: Antiviral assessment of some selected medicinal plants
Is part of: Science and practice 2016: the 7th international pharmaceutical conference, dedicated to the 240th anniversary of prof. Johann Friedrich Wolfgang, October 20-21, 2016, Kaunas, Lithuania : book of abstracts. Kaunas : Lithuanian university of Health Sciences, 2016
Extent: p. 35-35
Date: 2016
Keywords: Plants, medicinal;Phenols;Flavonoids;Antiviral agents;Chromatography, high pressure liquid;Gas chromatography-mass spectrometry
ISBN: 9789955154549
Abstract: This studies focuses on selected pathogenic virus, and antiviral natural compounds from medical plants. The lack of effective therapies and vaccines for several viral infections, and the rapid emergence of new drug-resistant viruses have urged a growing need for developing new and effective chemotherapeutic agents to treat viral diseases. recent advances in the understanding of both the cellular and molecular mechanisms of virus replication have provided the basis for novel therapeutic strategies. Several medicinal plants have been isolated for screening and identifying antiviral activity. Total amount of phenolic compounds, flavonoids and radical scavenging activity were determined spectrophotometriucally. Composition of the phenolic compounds in the extracts was analyzed chromatographically (HPLC and GC-MS). For evaluation of cytotoxicity effect and potential antiviral activity of medicinal and aromatic plants extracts using Vero cells. The Beaudette strain of Avian infectious bronchitis virus was used for antiviral properties testing. Antiviral effect shown Origanum vulgare L. Saturea montana L., Mentha piperita L., Melissa officinalis L., Thymus vulgaris L., Salvia officinalis L. and Desmondium canadence L
Affiliation(s): Botanikos sodas
Instrumentinės analizės APC
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija. Mikrobiologijos ir virusologijos institutas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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