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Type of publication: conference paper
Type of publication (PDB): Tezės kituose recenzuojamuose leidiniuose / Theses in other peer-reviewed publications (T1e)
Field of Science: Veterinarija / Veterinary (A002);Biologija / Biology (N010)
Author(s): Mickienė, Rūta;Drevinskas, Tomas;Maruška, Audrius Sigitas;Tiso, Nicola;Šalomskas, Algirdas;Lelešius, Raimundas;Karpovaitė, Agneta;Ragažinskienė, Ona;Kubilienė, Loreta
Title: Preliminary characterization and antiviral properties of some secondary metabolites in selected medicinal plants
Is part of: The vital nature sign [electronic resource] :10th international scientific conference, May 19-20, 2016 Vilnius, Lithuania : abstract book. Kaunas : Vytautas Magnus university, 2016, [no. 10]
Extent: p. 52-52
Date: 2016
Note: The research was granted by Research Council of Lithuania, project No. MIP-065/2015
Keywords: Plants, medicinal;Secondary metabolism;Herbal medicine;Viruses
Abstract: Medicinal plants have been used in traditional health care since prehistoric times and are still the most important health improvement resource for the vast majority of the population all over the world. World Health Organization emphasized importance of scientific research into herbal medicine. The use of antiviral synthetic drugs is often unsatisfactory and limited. Mutant viruses resistant to the existing antiviral agents arise upon treatment or these agents may cause side or toxic effects besides their high costs. In our research different medicinal plants, their parts and two types of propolis were selected for screening. Total phenolic content, total flavonoid content and radical scavenging activity was determined. The results indicated that optimal extrahent is 40%, vol. of ethanol – water mixture. Determined total phenolic content, total flavonoid content and radical scavenging activity indicated that extracts of Origanum Vulgare L., Mentha piperita L., Geranium macrorrhizum L., Melissa officinalis L. and Desmodium canadence L. contains highest amount of extractable phenolic compounds (7.31-7.16 rutin equivalents (mg/ ml) respectively), flavonoid content (2.14 - 1.51 rutin equivalents (mg/ml) respectively) and radical scavenging activity (11.98 - 12.22 rutin equivalents (mg/ml) respectively). Composition of the extracts is analyzed using HPLC. Evaluation of cytotoxicity effect (CE) was tested using Vero cells. Extract of Agastache foeniculum (Pursh) Kuntze showed the highest CE 6.32±0.13 log2 CE50. The research showed that all extracts have various not high CE and they can be used for testing of antiviral properties. The study of antiviral activity of extracts is in progress
Affiliation(s): Botanikos sodas
Instrumentinės analizės APC
Lietuvos sveikatos mokslų universitetas. Medicinos akademija
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija. Mikrobiologijos ir virusologijos institutas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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