Please use this identifier to cite or link to this item:https://hdl.handle.net/20.500.12259/54117
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dc.contributor.authorSaulė, Rita-
dc.contributor.authorSaulis, Gintautas-
dc.contributor.authorBatiuškaitė, Danutė-
dc.coverage.spatialLT-
dc.date.accessioned2018-10-07T00:05:14Z-
dc.date.available2018-10-07T00:05:14Z-
dc.date.issued2010-
dc.identifier.issn20293380-
dc.identifier.otherVDU02-000009201-
dc.identifier.urihttps://hdl.handle.net/20.500.12259/54117-
dc.description.abstractBleomycin alone was cytotoxic to mouse hepatoma MH-22A cells in vitro at concentrations above 10-20 nM. Exposure of cells to an electric pulse with the duration of 100 s and the amplitude of 2 kV/cm only did not reduce cell viability. Treatment of cells by an electric pulse in the presence of bleomycin greatly potentiated its cytotoxicity towards cells - the bleomycin concentration required to reduce cell survival by 50% was 3.8 nM only. It was obtained that the preincubation of mouse hepatoma MH-A22 cells with L-ascorbic acid at concentrations of 1 mM increased the number of electropermeabilized cells killed by bleomycinen
dc.description.sponsorshipBiologijos katedra-
dc.description.sponsorshipVytauto Didžiojo universitetas-
dc.format.extentp. 175-178-
dc.language.isoen-
dc.relation.ispartofBiomedical engineering - 2010 : proceedings of International Conference, 28-29 October 2010, Kaunas University of Technology. Kaunas : Technologija, 2010-
dc.subject.classificationStraipsnis recenzuojamoje Lietuvos tarptautinės konferencijos medžiagoje / Article in peer-reviewed Lithuanian international conference proceedings (P1e)-
dc.subject.otherBiochemija / Biochemistry (N004)-
dc.titleInfluence of ascorbic acid on the efficiency of electrochemotherapy with bleomycin in vitroen
dc.typeresearch article-
dcterms.bibliographicCitation9-
dc.date.updated2017-06-22T08:47Z-
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local.typeP-
item.fulltextNo Fulltext-
item.grantfulltextnone-
crisitem.author.deptVytauto Didžiojo universitetas-
crisitem.author.deptGamtos mokslų fakultetas-
crisitem.author.deptGamtos mokslų fakultetas-
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications
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