Please use this identifier to cite or link to this item:
Type of publication: research article
Type of publication (PDB): Straipsnis recenzuojamoje Lietuvos tarptautinės konferencijos medžiagoje / Article in peer-reviewed Lithuanian international conference proceedings (P1e)
Field of Science: Biochemija / Biochemistry (N004)
Author(s): Saulė, Rita;Saulis, Gintautas;Batiuškaitė, Danutė
Title: Influence of ascorbic acid on the efficiency of electrochemotherapy with bleomycin in vitro
Is part of: Biomedical engineering - 2010 : proceedings of International Conference, 28-29 October 2010, Kaunas University of Technology. Kaunas : Technologija, 2010
Extent: p. 175-178
Date: 2010
Abstract: Bleomycin alone was cytotoxic to mouse hepatoma MH-22A cells in vitro at concentrations above 10-20 nM. Exposure of cells to an electric pulse with the duration of 100 s and the amplitude of 2 kV/cm only did not reduce cell viability. Treatment of cells by an electric pulse in the presence of bleomycin greatly potentiated its cytotoxicity towards cells - the bleomycin concentration required to reduce cell survival by 50% was 3.8 nM only. It was obtained that the preincubation of mouse hepatoma MH-A22 cells with L-ascorbic acid at concentrations of 1 mM increased the number of electropermeabilized cells killed by bleomycin
Affiliation(s): Biologijos katedra
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

Show full item record
Export via OAI-PMH Interface in XML Formats
Export to Other Non-XML Formats

CORE Recommender

Page view(s)

checked on Jun 6, 2021


checked on Jun 6, 2021

Google ScholarTM


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.