Vytautas Magnus University Research Management System (VDU CRIS)
 
Use this url to cite publication: https://hdl.handle.net/20.500.12259/51702

Sema3A and NGF in regeneration of sensory axons

Type of publication
Konferencijų tezės nerecenzuojamame leidinyje / Conference theses in non-peer-reviewed publication (T2)
Author(s)
AuthorAffiliation
Kaselis, Andrius
Biologijos katedra / Department of Biology
LT
Treinys, Rimantas
Biologijos katedra / Department of Biology
LT
Kauno medicinos universiteto Kardiologijos institutas
LT
Title
Sema3A and NGF in regeneration of sensory axons
[en]
Part Of
Fifth conference of Lithuanian Neuroscience Association, 6-7 December, 2013, Vilnius, Lithuania : program and abstracts
Date Issued
Date
2013
Publisher
Vilnius : Lithuanian Neuroscience Association
Extent
p. 28-28
URI
URI
https://hdl.handle.net/20.500.12259/51702
Field of Science
Keywords (lt)
Keywords (en)
Abstract (en)

Regeneration of nervous system is complex and complicated process that involves neuron survival after injury as well as elongation of neurites and their guidance to final targets. Dorsal root ganglion (DRG) sensory neuron axon growth is highly impeded when they encounter neuronal growth cone-collapsing factor semaphorin3A (Sema3A) in both regeneration of adult nervous system and development of nervous system in embryonic stages. On the other hand, precise guidance of axon is mediated by many factors and increasing evidence shows that DRG axon development in both pathological and physiological conditions can be stimulated by nerve growth factor (NGF). The aim of this study was to evaluate the potential of increased NGF concentration to abolish Sema3A induced inhibitory responses in regenerating fifteen days old mouse embryo (e15) DRG axons in vitro. [...].

Type of document
type::text::conference output::conference proceedings::conference paper
Language
Anglų / English (en)
Coverage Spatial
Lietuva / Lithuania (LT)
Other Identifier(s)
VDU02-000014614