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Type of publication: Recenzuojamos išplėstinės tezės / Peer-reviewed extended theses (T1d)
Field of Science: Biochemija / Biochemistry (N004)
Author(s): Šulskytė, Indrė;Daugelavičius, Rimantas
Title: Multidrug resistance reason of MX - 1 cell culture
Is part of: Science and Practice 2015 : 6th International pharmaceutical conference, November 5-6, 2015, Kaunas, Lithuania : book of abstracts. Kaunas : Lithuanian university of Health Sciences, 2015
Extent: p. 18-19
Date: 2015
Keywords: Chemotherapy;Multidrug;MDR pumps
ISBN: 9789955154105
Abstract: Multidrug resistance in chemotherapy using drug is a major reason to failure treatment of cancer. The most exploring multi-drug resistance are related with drugs effluxion from cells in the presence of ATP-binding cassette (ABC) transporters The major MDR transporters is P - glycoprotein (P - gp/ ABCB1), multi-drug resistance protein 1 (MRP1/ ABCC1) and breast cancer resistance protein (ABCG2) (Giacomini ir kt., 2010). Molecular research with cancer cells can help to prevent and improve efficiency of this disease treatment.[...]
Affiliation(s): Biochemijos katedra
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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