Please use this identifier to cite or link to this item:https://hdl.handle.net/20.500.12259/45076
Type of publication: Straipsnis recenzuojamoje Lietuvos tarptautinės konferencijos medžiagoje / Article in peer-reviewed Lithuanian international conference proceedings (P1e)
Field of Science: Biologija / Biology (N010)
Author(s): Kačenauskaitė, Jovita;Žūkienė, Rasa
Title: Changes in myogenic stem cell respiration rate during differentiation
Is part of: The Vital Nature Sign : 3rd International Conference, Kaunas, Lithuania, May 22-23, 2009 : proceedings. Kaunas : Vytautas Magnus university, 2009
Extent: p. 113-115
Date: 2009
Keywords: Myogenic stem cell;Changes;Respiration rate
ISBN: 9789955125426
Abstract: Skeletal myoblast cells have high potential in cell therapy technologies, employing autonomous stem cells for the repair of the injured myocardium. We investigated the respiration rate of FR1 and FR3 cell culture, derived from rabbit skeletal muscle, during differentiation. Our results shown that differentiation decreased cellular respiration rate in both cell lines after 7 days differentiation by 54 % and 42 % in FR1 and FR3, respectively. Respiration rate of cell line FR1 characterized by higher passage number was lower by 22 % than the respiration rate of FR3. These data confirm other author’s observations with adult primate stromal cell line derived from adipose tissue that a high metabolic rate (higher oxygen consumption) together with the perinuclear arrangement of mitochondria may be valid indicators of stem cell differentiation competence, whereas departure from this profile indicate that cells are differentiating or perhaps becoming senescent
Internet: https://hdl.handle.net/20.500.12259/45076
Affiliation(s): Aplinkos tyrimų centras
Gamtos mokslų fakultetas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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