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Type of publication: research article
Type of publication (PDB): Straipsnis recenzuojamoje užsienio tarptautinės konferencijos medžiagoje / Article in peer-reviewed foreign international conference proceedings (P1d)
Field of Science: Biologija / Biology (N010)
Author(s): Danilevičiutė, Asta;Paulauskas, Algimantas;Gražulevičienė, Regina
Title: Xenobiotic metabolizing genes polymorphism in Kaunas city pregnant women
Is part of: Eco-Balt 2008: international conference, 2008 May 15-16, Riga (Latvia). Riga : Intego Plus, 2008
Extent: p. 52-53
Date: 2008
Keywords: Metabolic genes;Polymorphism;Pregnant women
Abstract: Little is know about genetic susceptibility to drinking water contaminants and pregnancy outcomes. We conducted a cross-sectional study to determine whether a difference exists in metabolic genes polymorphisms of users in women residing in different drinking water supply systems areas. The study population consisted of 120 randomly selected pregnant women served by four water treatment plants of Kaunas city. Mothers’ blood samples and questionnaire information were collected for testing gene-environment interactions. We used polymerase chain reaction (PSR) – based assays to genotype the polymorphism of metabolizing enzymes involved in the elimination of xenobiotic -glutathione-S-transferaze (GST). Comparison prevalence carriers and noncarriers of the GSTT1 variants revealed that there were not statistically significant differences across the gene status among women residing in different water treatment plants supplying zones
Affiliation(s): Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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