Physiological sensor data and clinical outcomes: insights into survival and disease progression in oncology

Abstract

<p> This study aimed to evaluate physiological data from various patient sensors and their associations with clinical endpoints such as survival and disease progression. The study ana lyzed data from living and deceased patients and those who progressed and did not progress during the course of the disease. First, graphs were created for each sensor to visualize the differences in curves between the living and deceased groups of patients. Analogous analysis was performed for patients who experienced disease progression compared to those who did not experience progression [1]. Overall survival (OS), follow-up period, and progression-free survival (PFS) were estimated using mean, standard deviation (SD), median, and min-max intervals. In addition, survival among deceased patients and time to progression among pro gressive patients were analyzed. Quality of life questionnaire data were correlated with sensor measures using both parametric and nonparametric methods in the entire patient sample [2]. Finally, the formulas and assumptions used in the analysis of each sensor were fully docu mented to ensure the reliability and reproducibility of the results. The results of the study will provide a better understanding of the interrelationships between physiological indicators and clinical endpoints and potentially contribute to the development of personalized medicine strategies in oncology [3].</p>