Photoplethysmographic assessment of the pulse wave: a blunted response to salbutamol in arterial hypertension and coronary heart disease
Author | Affiliation |
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Laucevičius, Aleksandras | |
Date | Volume | Issue | Start Page | End Page |
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2004 | 10 | 2 | 83 | 90 |
Objectives: A systemic vascular effect of beta2-adrenergic agonist salbutamol is partially mediated through the L-arginine–NO pathway. Therefore, the attenuation of photoplethysmographic digital volume pulse parameters under salbutamol inhalation could be used for the evaluation of endothelial function. The aim of the study was to estimate the vascular response to salbutamol in patients with arterial hypertension (AH) and coronary heart disease (CHD). Design and Methods: Totally 71 subjects were studied: 30 patients with AH, 26 patients with CHD and 15 healthy controls (C). All the subjects underwent the detailed clinical assessment and photoplethysmographic evaluation of the pulse wave response to 400 µg salbutamol inhalation. A portable photoplethysmograph Micro MedicalMP2000 ( Gillingham , Kent , United Kingdom ) was used for digital volume pulse analysis...