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Type of publication: Konferencijų tezės nerecenzuojamuose leidiniuose / Conference theses in non-peer-reviewed publications (T2)
Field of Science: Biologija / Biology (N010);Farmacija / Pharmacy (M003)
Author(s): Karosevičiūtė, Dovilė;Savickienė, Nijolė;Pavilonis, Alvydas;Ragažinskienė, Ona
Title: Determination of antimicrobial activity of raw material from Leonurus cardiaca L. and Leonurus sibiricus L
Is part of: Science and practice 2018: 9th international pharmaceutical conference, dedicated to the 100th anniversary of independent Lithuania's pharmacy, November 9, 2018, Kaunas, Lithuania : book of abstracts. Kaunas : Lietuvos sveikatos mokslų universitetas, 2018
Extent: p. 65-65
Date: 2018
Keywords: Leonurus;Plant extracts;Anti-infective agents
ISBN: 9789955155867
Abstract: Background: Leonurus cardiaca L. and Leonurus sibiricus L. – are herbaceous perennial plants in the Lamiaceae family. Various preparations of Leonurus L. herb have different antimicrobial activity [1,2]. In this study used medicinal raw: Leonurus sibiricus L. and Leonurus cardiaca L. obtained from Kaunas Botanical Garden of Vytautas Magnus University, Leonurus cardiaca L. - Mažeikiai district, Leonurus sibiricus L. – Mexico. Materials and methods: Leonurus L. medicinal raw was extracted by different solvents. The extraction method of ethanolic and methanolic extracts – percolation. The aqueous extract preparation - dry herb material was added into distilled water and the water was heated until it started boil. Antibacterial activity of ethanolic and methanolic extracts were performed by agar dilution in Petri dishes, aqueous using agar diffusion method. The minimum inhibitory concentration (MIC) was established. Results: Aqueous extracts inhibited Enterococcus faecalis and Candida albicans, methanolic and ethanolic - Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Bacillus cereus, Bacillus subtillis, Proteus vulgaris. All of methanolic and ethanolic extracts showed the least MIC value against Bacillus cereus. The lowest MIC value was determined of Leonurus cardiaca L ethanolic extract (Kaunas Botanical Garden of Vytautas Magnus University) - 4,25 mg/mL against Staphylococcus aureus and methanolic extract of Leonurus cardiaca L. (Mažeikiai district) - 5 mg/mL against Klebsiella pneumoniae. Conclusions: Methanolic and ethanolic extracts of Leonurus cardiaca L. showed better antimicrobial activity than methanolic and ethanolic extracts of Leonurus sibiricus L. Plants habitat did not had the significant effect on antimicrobial activity
Affiliation(s): Botanikos sodas
Lietuvos sveikatos mokslų universitetas. Medicinos akademija
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija. Mikrobiologijos ir virusologijos institutas
Vaistinių ir prieskon. augalų kol. Sektorius
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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