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Type of publication: conference paper
Type of publication (PDB): Konferencijų tezės nerecenzuojamuose leidiniuose / Conference theses in non-peer-reviewed publications (T2)
Field of Science: Biologija / Biology (N010)
Author(s): Tiso, Nicola;Mickienė, Rūta;Maruška, Audrius;Drevinskas, Tomas;Šalomskas, Algirdas;Lelešius, Raimundas;Karpovaitė, Agneta;Ragažinskienė, Ona;Kubilienė, Loreta
Title: Screening of non-volatile antiviral compounds from medicinal plants extracts
Is part of: ExTech 2016, ISSS 2016: 18th international symposium on advances in extraction technologies; 22nd international symposium on separation sciences, 3-6 July, 2016, Torun, Poland : abstract book / editors B. Buszewski, J. Kowalska. Torun: Nicolaus Copernicus University, 2016
Extent: p. 328-328
Date: 2016
Note: Acknowledgement: The research was granted by Research Council of Lithuania, project No. MIP-065/2015
Abstract: Several compounds with antiviral activity can be extracted from medicinal plants. Many of these plants have been used in the past to treat diseases of viral origin(1). There have been relatively few studies seeking antiviral agents from plants, and a number of compounds with antiviral effects have been extracted from various medicinal plants®. This research work is focused onto the investigation of the potential of non-volatile substances from plants and their extraction conditions for the preparation of antiviral agents. Sixteen different medicinal plants, their parts and two types of propolis were selected for screening. Firstly, extraction conditions of non-volatile compounds were screened: 3 pre-selected plants were extracted with 5 different ethanol - water mixtures (96%, 75%, 60 %, 40%, 20%, vol.) and bi-distilled water. The total content of flavonoids and phenolic compounds was determined as well as the radical scavenging activity. The results shown that optimal extraction solvent is the 40%, vol. of ethanol - water mixture. This extraction solvent was used to perform further investigations on all the samples. Determined total phenolic content, total flavonoid content and radical scavenging activity indicated that the highest amount of extractable phenolic compounds is present in the extracts of Origanum Vulgare L., Mentha piperita L., Geranium macrorrhizumL., Melissa officinalis L. and Desmodium canadence L. DC. Composition of the extracts was analyzed using HPLC
Affiliation(s): Botanikos sodas
Instrumentinės analizės APC
Lietuvos sveikatos mokslų universitetas. Medicinos akademija
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija
Lietuvos sveikatos mokslų universitetas. Veterinarijos akademija. Mikrobiologijos ir virusologijos institutas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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