Please use this identifier to cite or link to this item:https://hdl.handle.net/20.500.12259/48553
Type of publication: Tezės kituose recenzuojamuose leidiniuose / Theses in other peer-reviewed publications (T1e)
Field of Science: Biochemija / Biochemistry (N004)
Author(s): Mickienė, Rūta;Ragažinskienė, Ona;Maruška, Audrius
Title: Synergistic And Antagonistic Interactions Between Secondary Metabolites In Monarda Didyma L. And Angelica Archangelica L
Is part of: The vital nature sign [elektroninis išteklius] : 9th international scientific conference : abstract book. Kaunas : Vytautas Magnus university, 2015, [no. 9]
Extent: p. 34-34
Date: 2015
Keywords: Synergism;Secondary metabolites;Antimicrobial activities;Essential oils;Phenols
Abstract: This research focuses on synergistic and antagonistic interactions between secondary metabolites in Monarda didyma L., Angelica archangelica L. and antimicrobial activities of compounds isolated and identified from these species. The compounds pinene-α, terpinene-α, terpinene-γ, borneol, terpinen-4-ol, terpineol-α, estragole, methyl thymol, thymoquinone, caryophyllene, murolene-γ, germacrene, cadinene-δ, thymohydroquinone, phytone, hexadecanol, limonene, α-pinene, phellandrene-d-α, carophyllene-β, linalool, borneol, four macrocyclic lactones, various coumarins and other compounds were tested for their ability to compose the synergistic and antagonistic interactions. The antimicrobial activity of combinations secondary metabolites in Monarda didyma L. and Angelica archangelica L. originated from the sector of medicinal plants, Kaunas botanical garden of Vytautas Magnus University Lithuania, were tested by the method of series dilutions, against different bacteria species. This is a novel study of synergistic and antagonistic interactions between combinations plant secondary metabolites. Investigated microorganisms were Escherichia coli, Proteus vulgaris and Staphylococcus aureus with and without antibiotic resistances originating from livestock. The antimicrobial activities of extracts were described by determination of the minimal inhibitory concentration. The total amounts of phenolic compounds and total amounts of flavonoids were tested in the methanolic extracts of the plants. Identification of the phenolic compounds and evaluation of the radical scavenging activity of the compounds were performed by means of high performance liquid chromatography coupled with on-line 2.2-diphenyl-1-picrylhydrazyl radical scavenging reaction detection (HPLC-DPPH) analysis. The essential oils were analyzed by gas chromatography – mass spectrometry (GC-MS). [...]
Internet: https://hdl.handle.net/20.500.12259/48553
Affiliation(s): Biochemijos katedra
Gamtos mokslų fakultetas
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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