Please use this identifier to cite or link to this item:https://hdl.handle.net/20.500.12259/46136
Type of publication: Straipsnis kitose duomenų bazėse / Article in other databases (S4)
Field of Science: Medicina / Medicine (M001)
Author(s): Venskaitytė, Eurelija;Šventoraitytė, Jurgita;Poderytė, Kristina;Paulauskas, Algimantas
Title: Endogeninių ir egzogeninių veiksnių įtaka didelio meistriškumo sportininkų širdies ir kraujagyslių sistemos funkciniams rodikliams atliekant fizinius krūvius
Other Title: Influence of endogenous and egzogenous factors on peculiarities of cardiovascular reactions during exercise and recovery
Is part of: Sporto mokslas = Sport science. Vilnius : Lietuvos sporto informacijos centras, 2007, nr. 1(47)
Extent: p. 51-57
Date: 2007
Keywords: Genų polimorfizmas;Širdies ir kraujagyslių sistema;Endogeniniai ir egzogeniniai veiksniai;Gene polymorphism;Cardiovascular system;Endogenous and egzogenous factors
Abstract: Vieno iš molekulinių mechanizmų, reguliuojančių ŠKS (širdies ir krau jagyslių sistemos) funkcijas ir nulemiančių širdies pajėgumą, yra renino-angiotenzino sistema (RAS), o angiotenziną konvertuojančio fermento (AKF) genas – šios sistemos dalis. Šio tyrimo tikslas buvo įvertinti didelio meistriškumo sportininkų AKF I/D polimorfizmo ryšį su ŠKS funkciniais rodikliais.Tyrime dalyvavusiems sportininkams buvo atlikti genetiniai ir ŠKS funkcinių rodiklių vertinimo tyrimai. DNR buvo išskirta iš periferinio kraujo ląstelių ir polimerazinės grandininės reakcijos (PGR) metodu nustatyti AKF genotipai.[...]
One of the molecular mechanisms, which is a key component of the cardiovascular system functions regulation and determine its capacity or even development some of diseases – the renin-angiotensin system, within on of the proteins encoded by angiotensin-converting enzyme (ACE) gene. The aim of this study was to investigate the relation of different age athletesÿ the ACE I/D polymorphism to the functioning of their cardiovascular system during exercise workouts. Genetic and cardiovascular function researches in athletes were performed. DNA was extracted from peripheral blood cells and the ACE genotypes were identified by polymerase chain reaction (PCR) method. Standard 12-lead ECG and arterial blood pressure were registered during two exercise tests (of aerobic and anaerobic type). The results obtained during the study showed that in athletes of the II genotype subgroups were registered the less changes in heart rate and arterial blood pressure, in duration of JT intervals during booth exercise tests. JT/RR ratio indices differed during aerobic type of workout only. The highest values of this index were registered in both athletes groups in DD genotype subgroups, however recovery rate of this index were considerably slower comparing it to another two groups. The recovery of cardiovascular functional indices in both groups was slower in DD genotype subgroups. The study results suggest that genotype is an important egzogenous factor having influence on the speed of recovery of cardiovascular indices
Internet: http://www.loa.lt/images/dokumentai/sp_mokslas/SM_2007-1.pdf
http://www.loa.lt/images/dokumentai/sp_mokslas/SM_2007-1.pdf
Affiliation(s): Lietuvos kūno kultūros akademija
Vytauto Didžiojo universitetas
Appears in Collections:Universiteto mokslo publikacijos / University Research Publications

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